Mini-Reviews in Medicinal Chemistry Inhibitors of the HSP90 Molecular Chaperone: Attacking the Master Regulator in CancerĬurrent Topics in Medicinal Chemistry Interleukin-26, a Highly Cationic T-Cell Cytokine Targeting Epithelial CellsĪnti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Recent Progress in the Pharmacology of Imidazopyridines Vascular Disease Prevention (Discontinued) The Toolbox of Designing Nanoparticles for Tumors New Features in the Treatment of Androgen-Independent Prostate CancerĬurrent Pharmaceutical Design Targeting Chemokine Receptor CXCR4 for Treatment of HIV-1 Infection, Tumor Progression, and MetastasisĬurrent Topics in Medicinal Chemistry Recent Studies of QSAR on Inhibitors of Estrogen Receptor and Human Eosinophil PhosphodiesteraseĬurrent Computer-Aided Drug Design Bioavailability and Pharmacokinetics of Genistein: Mechanistic Studies on its ADMEĪnti-Cancer Agents in Medicinal Chemistry C6-Ceramide-Coated Catheters Promote Re-Endothelialization of Stretch- Injured Arteries Faculty of Pharmacy, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara 300041,RomaniaĪbstract: Cancer is still a leading cause of death worldwide, while most chemotherapies induce nonselective.Title:Gold Nanoparticles as Targeted Delivery Systems and Theranostic Agents in Cancer TherapyĪuthor(s): Alexandra Mioc, Marius Mioc, Roxana Ghiulai*, Mirela Voicu*, Roxana Racoviceanu, Cristina Trandafirescu, Cristina Dehelean, Dorina Coricovac and Codruta Soica Keywords: Gold nanoparticles, targeted delivery, theranostic, cancer therapy, magnetic resonance angiography,
Have pointed out data regarding the bioaccumulation and cytotoxicity of gold nanoparticles, but it hasīeen emphasized that size, dose, surface charge, sex and especially administration routes are very important Vitro anti-angiogenic, anti-proliferative and pro-apoptotic effects on various cell lines, such as humanĬervix, human breast, human lung, human prostate and murine melanoma cancer cells. Nevertheless, gold nanoparticles are therapeutic agents demonstrating its in Great contributions in the bioimaging field such as radiotherapy, magnetic resonance angiography and Vaccines), theranostics and agents in photothermal therapy. Playing many roles, such as targeted delivery systems (anticancer agents, nucleic acids, biological proteins, This review presents gold nanoparticles as versatile therapeutic agents Various shapes and sizes by a continuously developing set of means, including chemical, physical orĮco-friendly biological methods. Gold nanoparticles are easily synthesizable in Gold nanoparticles are nowadays in the spotlightĭue to their many well-established advantages. To address these problems, targeted nanoscience isĪn emerging field that promises to benefit cancer patients. Toxicity and severe systemic side effects. Cancer is still a leading cause of death worldwide, while most chemotherapies induce nonselective
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